منابع مشابه
Molecular biology tools
Need a replacement for a manufacturer’s protocol or product datasheet? Want to re-order an enzyme, but can’t find its catalogue number? As manufacturers scramble to put their product information online, much of it can now be tracked down on the web. In this article The spider takes a subjective look at the web offerings of some of the big suppliers of products for molecular biology (if we haven...
متن کاملTools of Genetic Research Molecular Biology
Re c e n t a dva n c e s in m o l e c u l a r b io l og y t ech n i q u e s p er m i t scientists to identify genetic contributions to alcoholism. Two main types of technology are commonly used to identify genes that cause or predispose a person to a disease: positional cloning techniques and candidate gene techniques. Positional cloning techniques allow disease genes to be identified based sol...
متن کاملDegenerate Primer Design Using Computational Tools Computational Molecular Biology
The polymerase chain reaction (PCR) is widely used to uncover new information about genes and genomes, but is limited in that it is highly dependent on the use of specific and sensitive primers to yield good results. Primers can target a specific, known sequence, but what is often more interesting is the use of degenerate primers to target unknown sequences. Degenerate primers are designed base...
متن کاملCovalently linked complementary oligodeoxynucleotides (splinkers) as tools for molecular biology.
MOU*MC«« Self-complementary primer l inkers ("splinkers") speci f ica l ly jo in to restr icted DMA. These oligonucleotides consist of an inverted repeat sequence which forms a double stranded hairpin structure containing a known rest r ic t ion s i te (RS). This bu i l t i n res t r ic t ion s i te enables their specific release from the restr icted DNA fragment. The schematic diagram shows a ...
متن کاملAptamers as tools in molecular biology and immunology.
We have listed and described recent promising developments in the field of aptamer research. The properties and the application potential of aptamers propose an exciting future for aptamers either in the clinic or as research tools for various purposes. We have reviewed exciting examples in which the SELEX technology was applied to obtain promising tools that may help to facilitate our understa...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1996
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)70657-x